2-[benzyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid
NALPHA-9-Fluorenylmethoxycarbonyl-N-benzylglycine
CAS: 141743-13-7
Molecular Formula: C24H21NO4
2-[benzyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid - Names and Identifiers
2-[benzyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid - Physico-chemical Properties
| Molecular Formula | C24H21NO4 |
| Molar Mass | 387.43 |
| Density | 1.285±0.06 g/cm3(Predicted) |
| Boling Point | 604.0±44.0 °C(Predicted) |
| pKa | 3.89±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ |
2-[benzyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid - Risk and Safety
| HS Code | 29225090 |
2-[benzyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid - Introduction
Fmoc-N-benzylglycine is an amino acid protecting group whose chemical name is 9-fluorobarbyl-dimethoxycarbazenylglycine, abbreviated as Fmoc-Bn-Gly-OH. The following is a description of the properties, uses, preparation and safety information of Fmoc-N-benzyl glycine:
Properties: Fmoc-N-benzylglycine is a white or yellowish solid with a relative molecular mass of 383.38. It can be dissolved in common organic solvents (such as dimethylformamide, dichloromethane, etc.), but is insoluble in water.
Purpose: Fmoc-N-benzyl glycine is mainly used in solid phase synthesis (SPPS) as a protective group of amino acids. It can protect the amine group of glycine to prevent non-specific reactions during the reaction. In the process of solid phase synthesis, Fmoc-N-benzyl glycine can be used on each amino acid of the synthetic polypeptide chain, and the expansion of the synthetic polypeptide chain can be realized by controlling the safe removal of the protecting group.
Preparation method: The synthesis method of Fmoc-N-benzylglycine is complicated, and the final product needs to be obtained through a multi-step reaction. First, N-benzylglycine was synthesized by an appropriate synthetic route. Then, N-benzylglycine is reacted with Fmoc-Cl to produce Fmoc-N-benzylglycine. The synthesis requires proper protection and deprotection reactions to ensure product purity and activity.
Safety Information: Fmoc-N-Benzylglycine is generally considered to be relatively safe under normal operating conditions. However, it is still a chemical, and the following safety precautions need to be paid attention to: avoid direct contact with skin and eyes, wear protective gloves and goggles if necessary; provide good ventilation during operation to avoid inhalation of dust generated. During handling and storage, chemical safety practices should be followed to ensure proper packaging and sealing, away from ignition and oxidizing agents. In case of ingestion or inhalation, seek medical advice immediately.
Properties: Fmoc-N-benzylglycine is a white or yellowish solid with a relative molecular mass of 383.38. It can be dissolved in common organic solvents (such as dimethylformamide, dichloromethane, etc.), but is insoluble in water.
Purpose: Fmoc-N-benzyl glycine is mainly used in solid phase synthesis (SPPS) as a protective group of amino acids. It can protect the amine group of glycine to prevent non-specific reactions during the reaction. In the process of solid phase synthesis, Fmoc-N-benzyl glycine can be used on each amino acid of the synthetic polypeptide chain, and the expansion of the synthetic polypeptide chain can be realized by controlling the safe removal of the protecting group.
Preparation method: The synthesis method of Fmoc-N-benzylglycine is complicated, and the final product needs to be obtained through a multi-step reaction. First, N-benzylglycine was synthesized by an appropriate synthetic route. Then, N-benzylglycine is reacted with Fmoc-Cl to produce Fmoc-N-benzylglycine. The synthesis requires proper protection and deprotection reactions to ensure product purity and activity.
Safety Information: Fmoc-N-Benzylglycine is generally considered to be relatively safe under normal operating conditions. However, it is still a chemical, and the following safety precautions need to be paid attention to: avoid direct contact with skin and eyes, wear protective gloves and goggles if necessary; provide good ventilation during operation to avoid inhalation of dust generated. During handling and storage, chemical safety practices should be followed to ensure proper packaging and sealing, away from ignition and oxidizing agents. In case of ingestion or inhalation, seek medical advice immediately.
Last Update：2024-04-09 21:01:54
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Product Name: Fmoc-N-benzylglycine Visit Supplier Webpage Request for quotation
CAS: 141743-13-7
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 141743-13-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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